Disinfectant Residue Removal Recommendations

There are many options for developing a residue removal step to a cleaning and disinfection program. Below are examples of steps that can be taken to remove residues from the controlled area or cleanroom. These are general recommendations and are to be used as guidance independent of the disinfectant used. Always follow site Standard Operating Procedures (SOPs). Solutions used may be dependent upon the surfaces to be cleaned, environmental versus product contact.

Residue Removal Steps with Dry Wipe on Wet Surface

1. Allow disinfectant to meet validated wet contact time.
2. Wipe wet disinfectant with dry wipe or mopping tool.
3. Remove excess residue with 70% presaturated wipe

Residue Removal Steps with Presaturated Wipe on Dry Surfaces

1. Allow disinfectant to meet validated wet contact time.
2. Let surface dry.
3. Remove disinfectant residue with presaturated 70% IPA wipe (may have to be repeated depending on the severity of the residue).

Residue Removal Step for Floors, Walls, Ceilings for Dry Surfaces with WFI

1. Allow disinfectant to meet validated wet contact time.
2. Let surface dry.
3. Apply WFI to surface using mop or sprayer (if sprayer is used, ensure water does not get into hard to reach places, if there is a risk for that, it is not recommended).
4. Mop or vacuum until dry.

Residue Removal Step for Floors, Walls, Ceilings for Dry Surfaces with Detergent

1. Allow disinfectant to meet validated wet contact time.
2. Let surface dry.
3. Apply detergent to surface using mop.
4. WFI rinse with mop.
5. Follow up dry mop or vacuum.